CBDa: Can This Cannabis Compound Help Fight COVID?

Cannabidiol (CBD) has taken the wellness world by storm, but have you heard of its lesser-known cousin, CBDa (cannabidiolic acid)? This newsletter explores the exciting potential of CBDa and what this precursor molecule might offer.

What is CBDa?

CBDa is the precursor to CBD. It’s the natural form found in the cannabis plant before it’s exposed to heat or light, which triggers a process called decarboxylation, converting CBDa into CBD.

CBDa vs. CBD: Key Differences

While structurally similar to each other, CBDa and CBD have distinct characteristics:

  • Chemical Structure: CBDa has an extra carboxylic acid group compared to CBD. This slight difference significantly impacts how they interact with the body.
  • Bioavailability: CBDa may be more bioavailable than CBD, meaning it might be absorbed more efficiently by the body. This may be due to the different chemical structure of the molecules. Some sources suggest a drastically higher percentage of bioavailability for all acidic/precursor forms of cannabinoids.
  • Mechanism of Action: Here’s where it gets interesting! CBD primarily interacts with the body’s endocannabinoid system indirectly. It influences the activity of naturally occurring cannabinoids without directly binding to receptors. CBDa, on the other hand, might interact with enzymes that break down these natural cannabinoids, potentially allowing them to exert a stronger effect. Additionally, some research suggests CBDa may directly bind to certain receptors, although more evidence is needed.

Potential Benefits (Early Research):

While research is still in its early stages, some studies suggest this fascinating cannabis molecule might be beneficial for:

  • Inflammation: CBDa may possess anti-inflammatory properties potentially helpful for conditions like arthritis and inflammatory bowel disease.
  • Nausea: Early research suggests CBDa could be effective in reducing nausea and vomiting.
  • Anxiety: Due to its influence on the endocannabinoid system, CBDa can potentially reduce anxiety levels.
  • Virus Protection: In the next section, we explore this exciting cannabinoid’s potential to prevent viruses from entering cells.

Can CBDa Protect Against Viruses like COVID-19?

There is emerging research suggesting CBDa might offer some protection against certain viruses, including COVID-19. Here’s what we know so far:


Promising Study: A study by Oregon State University investigated the potential of CBDa and other cannabinoids (such as CBGa) to inhibit COVID-19 infection.


Mechanism: The study found that CBDa might prevent the virus from entering cells by binding to its spike protein, the part it uses to attach and invade healthy cells. This binding action could potentially block the virus’s ability to unlock the cell and inject its genetic material, effectively stopping the infection process in its tracks.


Important Caveats: It’s crucial to remember that this was a cell-based study, and more research is needed to confirm these effects in humans. Additionally, the study focused on preventing infection, not treating an existing case. It’s still important to take other precautions against viruses, such as eating a healthy, balanced diet to support your immune system, getting plenty of sleep, and exercising caution in heavily populated areas where you’re more likely to be exposed to viruses.

Thanks for Reading!

Stay healthy, FlowerChild family! We appreciate every one of you. If you’re interested in trying out this powerful cannabis molecule for yourself, click here to go to the product page.

FlowerChild is a small family business committed to bringing you the best cannabis oils available. The vast majority of our products are made with whole-plant, full-spectrum extracts that preserve as many of the plant’s healing compounds as possible. All our products are hand crafted in small batches, ensuring their freshness and potency, and we are happy to assist with any questions you might have. We’re also big fans of sharing all the holistic health information that we can to help you learn how to live a healthier life. Be sure to subscribe to our newsletter for exclusive sales and informative health emails!